| Date | Location | Result | |
| Nov 18,2000 | Johnson City, Tenn | East Tennessee State 55, Charleston Southern 7 | Box score |
| Nov 11, 2000 | Lynchburg, Va | Charleston Southern 25, Liberty 0 | Box score |
| Nov 04, 2000 | Birmingham, Ala. | Samford 21, Charleston Southern 14 | Box score |
| Oct 28, 2000 | Charleston, SC | Elon 28, Charleston Southern 12 | Box score |
| Oct 21, 2000 | Lexington, Va. | VMI 40, Charleston Southern 7 | Box score |
| Oct 14, 2000 | Clarksville, Tenn. | Charleston Southern 42, Austin Peay 20 | Box score |
| Oct 07, 2000 | Charleston, SC | Charleston Southern 28, Jacksonville 22 | Box score |
| Sep 23, 2000 | Charleston, SC | Wofford 24, Charleston Southern 10 | Box score |
| Sep 16, 2000 | Charleston, SC | Charleston Southern 30, West Virginia State 6 | Box score |
| Sep 09, 2000 | Clinton, SC | Presbyterian 28, Charleston Southern 13 | Box score |
| Sep 02, 2000 | Charleston, SC | Charleston Southern 58, Guilford 0 | Box score |